Isotope Recovery and Production

Groves Oklo Isotopes building in Texas under a clear sky

Building a domestic supply of critical nuclear materials

At Oklo, we are developing capabilities to strengthen U.S. supply chains for high-value isotopes used in medicine, space, advanced manufacturing, research, and national security. We are pairing disciplined execution, including licensed handling, laboratory operations, and planned pilot-scale production, with a path to scale into purpose-built facilities over time.

What is Oklo’s isotope business?

Our isotope program focuses on recovering, purifying, and producing key isotopes. Current domestic supply is constrained by limited production capacity, aging infrastructure, and complex logistics. Oklo’s program is designed to move from material handling and laboratory processing to pilot production and ultimately to commercial-scale production that can support long-term demand.

How it works

Material recovery and purification

Recover isotope-bearing material that is currently stored, underutilized, or treated as waste, and process it into usable, well-characterized products suitable for further use or distribution

Purpose-built isotope production

Use reactors and associated processing facilities to produce, separate, package, and prepare isotopes for customers

Isotope recovery through fuel recycling

Recover selected high-value isotopes through advanced fuel-recycling processes

Designed for execution and scale. Oklo’s isotope strategy is built to scale:

Start with licensed capabilities and operating procedures that enable real-world handling and processing
Use pilot operations to generate data, refine workflows, and harden quality assurance and quality-control programs
Develop purpose-built facilities as customer demand and commercial partnerships mature

The goal is to establish a reliable domestic pipeline with consistent inputs, controlled processing, and predictable output.